职业卫生

贾强

2024-03-07

贾强，研究员，山东省职业卫生与职业病防治研究院副院长，山东第一医科大学公共卫生与健康管理学院副院长（兼），山东第一医科大学博士研究生导师，博士后合作导师。主持完成国家自然科学基金面上项目、山东省自然科学基金等科研课题10余项，参与国家卫生行业专项、国家“十四五”重点研发计划等大型课题。荣获中华预防医学会科学技术一等奖、三等奖，中国职业健康安全协会科学技术一等奖等科研成果奖励8项。被评为齐鲁卫生与健康领军人才，山东省高等学校青年创新团队带头人，以第一或通讯作者在Environmental Science & Technology、Environmental pollution、Environmental Research等杂志发表SCI收录论文30余篇，为首和参与修订国家卫生行业标准3项。兼任山东预防医学会卫生毒理分会主任委员、中国毒理学会工业毒理委员会常务委员、山东省干细胞学会干细胞工程技术标准专业委员会副主任委员、《中国职业医学杂志》《中国工业医学杂志》编委等。

研究方向：职业性呼吸系统疾病发病机制及诊疗技术研究；主要化学毒物（苯、铅等）中毒机制及干预药物筛选；新型环境污染物的健康效应研究。

［教育简历］

2010.09-2013.07中国疾病预防控制中心，卫生毒理学，博士；

2002.09-2005.07山东省医学科学院，劳动卫生与环境卫生学，硕士；

1997.09-2002.07山东大学，公共卫生学院，学士

［工作简历］

2024-01至今，山东第一医科大学，山东省职业卫生与职业病防治研究院，研究员

2019.03—2023.12，山东第一医科大学，山东省职业卫生与职业病防治研究院，副研究员

2014.10—2019.02，山东省医学科学院，山东省职业卫生与职业病防治研究院，副研究员

2014.03—2017.06，山东中医药大学，中西医结合基础，博士后流动站

2008.08—2014.09，山东省医学科学院，山东省职业卫生与职业病防治研究院，助理研究员

2005.07—2008.07，山东省医学科学院，山东省职业卫生与职业病防治研究院，研究实习员

［社会兼职］

山东预防医学会卫生毒理分会主任委员

中国毒理学会工业毒理委员会常务委员

山东省实验动物学会常务理事

山东省公共卫生学会卫生毒理分会常务委员

中国环境诱变剂学会生物标志物委员会委员

［近五年代表性科研成果］

1. Yang X, Dong S, Xing C, Li C, Bo C, Meng X, Liu Z, Shao H, Li M*, Jia Q*. Ferroptosis is involved in the benzene-induced hematotoxicity via mitochondrial ROS-ferritinophagy pathway [J]. Environ Pollut. 2025,(376)：126379. IF=7.6

2. Shuangshuang Pu, Xiangjing Meng, Yushan Shi, Ning Huang, Chunlai Zhang, Aimei Pang, Hua Shao*, Qiang Jia*. Fermented Cordyceps Powder alleviates silica-induced inflammation and fibrosis by inhibiting M1 macrophage polarization via the HMGB1-TLR4-NF-κB pathway [J]. Journal of Ethnopharmacology. 2025(345) :119631.IF=4.8

3. Li，C, Chen X, Du ZvGeng X, Li M, Yang X, Bo C, Jia Q*, Yu G*, Shi L*. Inhibiting ferroptosis in brain microvascular endothelial cells: A potential strategy to mitigate polystyrene nanoplastics‒induced blood‒brain barrier dysfunction. [J].Environmental Research. 2024, 20(250):118506. IF=8.3

4. Xiangjing Meng, Sumei Guo, Xiaoxia Zhang, Bo Jiao, Xiaohan Yang, Ming Li, Chao Li, Jin He, Shangya Chen, Cheng Peng, Hua Shao*, Qiang Jia*. HMGB1 inhibition reduces TDI-induced occupational asthma through ROS/AMPK/autophagy pathway[J]. Ecotoxicology and Environmental Safety, 2023(266):115575. IF=7.129

5. Xiangjing Meng, Yanhua Wang, Ting Wang, Bo Jiao, Hua Shao, Qiang Jia*, Huawei Duan* . Particulate Matter and Its Components Induce Alteration on the T-Cell Response: A Population Biomarker Study [J], Environmental Science & Technology, 2023, 57(1): 375-384. IF=11.357

6. Xiaohan Yang, Shuangyan Dong, Chao Li, Ming Li, Caihong Xing, Jin He, Cheng Peng, Hua Shao*, Qiang Jia*. Hydroquinone triggers pyroptosis and endoplasmic reticulum stress via AhR-regulated oxidative stress in human lymphocytes[J]. Toxicol Lett, 2023, (376): 39–50. IF=4.372

7. Ming Li, Zhifeng Yang, Zhaoyuan Song, Cunxiang Bo, Shuo Wang, Qiang Jia*. ATM deficiency aggravates the progression of liver fibrosis induced by carbon tetrachloride in mice[J]. Toxicology, 2023, 15(484):153397. IF=4.571

8. Shuangshuang Pu, Zhifeng Yang, Xiaofeng Zhang, Ming Li, Na Han, Xiaohan Yang, Jin He, Gongchang Yu, Xiangjing Meng, Qiang Jia*, Hua Shao*. Fermented cordyceps powder alleviates silica-induced pulmonary inflammation and fibrosis in rats by regulating the Th immune response [J]. Chin Med, 2023, 18(1): 131. IF=4.9

9. Xiaohan Yang, Chao Li, Gongchang Yu, Lei Sun, Sumei Guo, Linlin Sai, Cunxiang Bo, Caihong Xing, Hua Shao*, Cheng Pengc*, Qiang Jia*. Ligand-independent activation of AhR by hydroquinone mediates benzene-induced hematopoietic toxicity [J]. Chemico-Biological Interactions. 2022(355):109845. IF=5.192

10. Shu-xian Li , Chao Li , Xin-ru Pang , Juan Zhang , Gong-chang Yu *, Abrey J. Yeo ,Martin F. Lavin , Hua Shao , Qiang Jia * , Cheng Peng * Metformin Attenuates Silica-Induced Pulmonary Fibrosis by Activating Autophagy via the AMPK-mTOR Signaling Pathway [J]. Frontiers in Pharmacology，2021(12):719589. IF=5.81

11. Xinru Pang; Linlin Shao; Xiaojuan Nie; Haiyue Yan; Chao Li; Abrey J Yeo; Martin F Lavin; Qing Xia; Hua Shao; Gongchang Yu*; Qiang Jia*; Cheng Peng*; Emodin attenuates silica-induced lung injury by inhibition of inflammation，apoptosis and epithelial-mesenchymal transition [J]. Int Immunopharmacol，2021(91): 107277. IF=4.932

12. Bo Jiao , Sumei Guo , Xiaohan Yang , Lei Sun , Linlin Sai , Gongchang Yu , Cunxiang Bo ,Yu Zhang , Cheng Peng , Qiang Jia,*, Yufei Dai. The role of HMGB1 on TDI-induced NLPR3 inﬂammasome activation via ROS/NF-κB pathway in HBE cells [J]. International Immunopharmacology. 2021(98): 107859. IF=4.932

13. Bo Jiao, Yujun Chen, Yuting Yang, Linlin Sai, Gongchang Yu, Cunxiang Bo, Yu Zhang, Cheng Peng, Qiang Jia*, Hua Shao*, Toluene diisocyanate-induced inflammation and airway remodeling involves autophagy in human bronchial epithelial cells [J]. Toxicology In Vitro, 2021(70): 105040. IF=3.50